Clinical Data

The following articles contain more information about the ingredients in the Hubris products and in some cases we have included reports from respected publications.

Glucosamine Sulphate: the key to trouble-free joints

Glucosamine sulphate is a synthesised salt of glucosamine and is a major component of soft tissues such as cartilage, ligament, tendon and skin. Studies have shown that as we age we lose the ability to manufacture glucosamine sulphate. As a result the healing rate of soft tissue injury slows down. Because they assist in the regeneration of cartilage and improve joint function, glucosamine sulphate supplements are now widely used in the treatment of osteoarthritis.

Helping to heal the natural way

Until recently, the only treatments available for joint inflammation, injuries and disease were anti-inflammatories, steroid injections or surgery. Glucosamine sulphate is now proving to be a natural therapy preferred by many patients as an alternative to - or in conjunction with - conventional treatments.

Some orthopaedic surgeons now recommend the use of glucosamine sulphate after surgery, to assist the healing process. Clinical trials show that glucosamine sulphate can provide better long term pain relief of arthritis than anti-inflammatories, while actually promoting healing.

Successful clinical trials!

Glucosamine Sulphate proves worth in long term osteoarthritis trial. The latest research findings on glucosamine sulphate were recently detailed in a landmark study published in The Lancet, the well known British medical journal.

In a placebo controlled trial with colleagues in Britain, Italy and the United States, the researchers treated 212 patients suffering from knee osteoarthritis either with 1500mg oral glucosamine sulphate, or a placebo, daily for three years. Weight bearing, ante posterior radiographs of each knee in full extension were taken at enrolment and after one and three years.

Researchers found no significant joint-space loss after three years in the 106 patients treated with glucosamine sulphate. However, among the 106 patients on a placebo there was a progressive joint space narrowing, with a mean joint-space loss of 0.31mm. Those who were treated had a 20 to 25 per cent improvement in symptoms, compared with a slight worsening of symptoms in the placebo group.

Dr Tim McAlindon, of the Arthritis Centre, Boston University Medical Centre, says "the results are impressive; patients assigned to glucosamine experienced significant improvements in pain and disability that were sustained for the 3 years of the study, whereas the scores among the placebo group worsened. Further more, adverse event rates were not higher than those associated with placebo.

These findings are consistent with those seen in previous symptom based studies of glucosamine. Even though the effect sizes are modest, glucosamine sulphate could play an important part in the longterm therapy of Osteoarthritis."

Perna Mussel - overview

A tiny mussel from New Zealand is making waves in the sea of natural remedies for arthritic relief. Perna-canaliculus, in the freeze-dried form, is gaining fame as arthritis victims claim a lessening of joint stiffness and inflammation.

The Perna Mussel (also known as the New Zealand green lipped mussel) is a tiny animal that is part of the basic food chain, concentrating mineral and nutritional elements from the sea. As it feeds, the mussel filters 15 to 20 gallons of sea water per day, efficiently converting plankton, algae, and kelp into protein, carbohydrates, mineral, vitamins, and trace elements.

How it works in the body

In arthritic conditions, the membrane surrounding the joint becomes thin and porous. The synovial fluid then seeps out through the porous membrane, resulting in discomfort and swelling. When the lubricating fluid is thickened, it cannot leach out. Thus, joint cushioning and lubrication are normalized.

In addition to balancing the lubricating fluids of the body, the richness of mucopolysaccharides concentrated in the perna mussel contributes to its effectiveness in healing soft tissue, torn tendons, and bruises.

The most important thing to note about perna mussel is that it is a source of natural minerals and that these minerals are chelated by the mussel itself, thus ensuring that the body will assimilate them.

The mucopolysaccharide, hyaluronic acid is one portion of the Protein- polysaccharide complex present in PERNA. These complexes in the mussel are associated with protective support and lubrication systems as well as egg jellies and capsules. Providing hyaluronic acid, PERNA aids the body in maintaining synovia fluid viscosity, important for lubrication of bone joint linings. In both the human and animal system, relief from pain and stiffness associated with degenerative joint disease is obtained with regular ingestion of PERNA. As a result, mobility increases and the mental and physical outlook of the individual is brightened.